HDAC8 polyclonal antibody

• Background :

  Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. May play a role in smooth muscle cell contractility.

• Structure Composition :

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Product Name Alternative :

  HDAC8; HDACL1; CDA07; Histone deacetylase 8; HD8

• Swiss Prot :

  Q9BY41

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthesized peptide derived from human HDAC8

• Conjugation :

  Unconjugated

• Applications :

  WB, IP, FC

• Dilution :

  WB: 1/500-1/1000 IP: 1/20 FC: 1/50-1/100

• Purity :

  Affinity Purified

• Modification :

  Unmodified

• Molecular Weight :

  Calculated MW: 42 kDa; Observed MW: 42 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  IgG

• Applications Notes :

  Western blot analysis of HDAC8 in HeLa lysates using HDAC8 antibody.

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4