MonoMethyl-Histone H2B (Arg79) polyclonal antibody

• Background:

  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

• Structure Composition:

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Product Name Alternative:

  H2BR79me; H2B; H2BQ; GL105; H2B.1; H2BFQ; H2BGL105

• Swiss Prot:

  Q16778

• Reactivity:

  Human, Mouse

• Immunogen:

  A synthesized peptide derived from human Histone H2B (mono methyl R79)

• Conjugation:

  Unconjugated

• Applications:

  WB

• Dilution:

  WB: 1/500-1/1000

• Purity:

  Affinity Purified

• Modification:

  Methylated

• Molecular Weight:

  Calculated MW: 14 kDa; Observed MW: 14 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of Histone H2B in HeLa lysates using MonoMethyl-Histone H2B antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4