FOXO1 polyclonal antibody

• Background :

  Transcription factor which acts as a regulator of cell responses to oxidative stress. In the presence of KIRT1, mediates down-regulation of cyclin D1 and up-regulation of CDKN1B levels which are required for cell transition from proliferative growth to quiescence.

• CAS Number :

  9007-83-4

• Structure Composition :

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Product Name Alternative :

  FOXO1; FKHR; FOXO1A; Forkhead box protein O1; Forkhead box protein O1A; Forkhead in rhabdomyosarcoma

• Swiss Prot :

  Q12778

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthesized peptide derived from human FoxO1a

• Conjugation :

  Unconjugated

• Applications :

  WB, IHC-P, ICC/IF

• Dilution :

  WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

• Purity :

  Affinity Purified

• Modification :

  Unmodified

• Molecular Weight :

  Calculated MW: 70 kDa; Observed MW: 70 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  IgG

• Applications Notes :

  Western blot analysis of FoxO1a in Jurkat, THP-1, SKOV-3, MCF-7 and Hela lysates using FOXO1 antibody.

• Host or Source :

  Rabbit