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P300 polyclonal antibody

CAT: 0384-BZ16469-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BZ16469-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
EP300: E1A binding protein p300. This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
EP300; P300; Histone acetyltransferase p300; p300 HAT; E1A-associated protein p300
Swiss Prot
Q09472
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human p300.
Conjugation
Unconjugated
Applications
ICC/IF, WB, IHC-F, IHC-P, ELISA
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 264 kDa; Observed MW: 300 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of p300 in HELA, 293T, 823AV lysates using p300 antibody.
Host or Source
Rabbit

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MBS8526673-01p300 Polyclonal Antibody

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