Cleaved-Notch1 polyclonal antibody

CAT: 0384-BZ16348-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BZ16348-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting.
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
NOTCH1; TAN1; Neurogenic locus notch homolog protein 1; Notch 1; hN1; Translocation-associated notch protein TAN-1
Swiss Prot
P46531
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Notch 1. AA range:1735-1784
Conjugation
Unconjugated
Applications
WB, ICC/IF, IHC-F, IHC-P, ELISA
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
Purity
Affinity Purified
Modification
Cleaved
Molecular Weight
Calculated MW: 273 kDa; Observed MW: 110 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of Cleaved-Notch1 in various lysates using Cleaved-Notch1 antibody.
Host or Source
Rabbit

Related Products

CatalogName
BS80038-01Notch1 polyclonal antibody
BS80204Notch1 polyclonal antibody
BS80037-01Notch1 polyclonal antibody
BS67677NOTCH1 polyclonal antibody
BS80511Notch1 polyclonal antibody
BS80318Notch1 polyclonal antibody
BS7018-01Cleaved-Notch 1 (V1754) polyclonal antibody
BS7043-01Cleaved-Notch 2 (A1734) polyclonal antibody
BS90309Cleaved PARP polyclonal antibody
MB11318-01Notch1 monoclonal antibody

Alternative Products

CatalogName
E10G20028Cleaved-Notch1 Rabbit Polyclonal Antibody
E-AB-30054-01Cleaved-NOTCH1 (V1754) Polyclonal Antibody
JOT-AP03842-01NOTCH1 (Cleaved-Val1711) Rabbit Polyclonal Antibody
MBS8571322-01NOTCH1 Polyclonal Antibody
OASG05119-100ULNOTCH1 Antibody (Cleaved-Val1754)
A10676-50UGCleaved-NOTCH1 (V1754) Antibody
OAAF05328-100UGNOTCH1 (Cleaved-Val1754) Antibody
L0409-01NOTCH1 (Cleaved-Val1711) Antibody
CST 55895SCleaved Notch1 (Val1744) Matched Antibody Pair
CST 8216SPhosphoPlus® Notch1 (Cleaved, Val1744) Antibody Duet

Popular Products