SOD2 polyclonal antibody

• Background:

  SOD-2 is a homotetrameric manganese enzyme (also known as MnSOD) that functions in the mitochondrion. ROS are implicated in a wide range of degenerative processes, including Alzheimer’s disease, Parkinson’s disease and ischemic heart disease. Homozygous mutant mice, which lack SOD-2, exhibit dilated cardiomyopathy, accumulation of lipid in liver and skeletal muscle, metabolic acidosis, oxidative DNA damage and respiratory chain deficiencies in heart and skeletal muscle.

• Structure Composition:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

• Product Name Alternative:

  IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD; SOD2

• Swiss Prot:

  P04179

• Reactivity:

  Human, Mouse, Rat, Monkey

• Immunogen:

  Synthetic peptide.

• Conjugation:

  Unconjugated

• Applications:

  WB

• Dilution:

  WB: 1/500-1/1000

• Purity:

  Affinity Purified

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 25 kDa; Observed MW: 25 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of SOD2 in 293, COS7, C6, 3T3 and Hela lysates using SOD2 antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4