Collagen VIII alpha 2 polyclonal antibody

• Background:

  This gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. Alternative splicing results in multiple transcript variants.

• Structure Composition:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

• Product Name Alternative:

  Collagen alpha-2 (VIII) chain (Endothelial collagen)

• Swiss Prot:

  P25067

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthesized peptide derived from human COL8A2. at AA range: 611-660

• Conjugation:

  Unconjugated

• Applications:

  WB, ELISA

• Dilution:

  WB: 1/500-1/1000 ELISA: 1/10000

• Purity:

  Affinity Purified

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 67 kDa; Observed MW: 80 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of Collagen VIII alpha 2 in hela, 3T3 lysates using Collagen VIII alpha 2 antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4