Smad1/5/9 polyclonal antibody

• Background:

  Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD) . SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP) -mediated cardiac-specific gene expression.

• Structure Composition:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

• Product Name Alternative:

  Mothers against decapentaplegic homolog 1/5/9; MAD homolog 1; Mothers against DPP homolog 1; JV4-1; Mad-related protein 1; SMAD family member 1; SMAD 1/5/9; Smad1; hSMAD1; Transforming growth factor-beta-signaling protein 1; BSP-1

• Swiss Prot:

  Q15797/Q99717/O15198

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthesized peptide derived from human Smad1/5/9. at AA range: 291-340

• Conjugation:

  Unconjugated

• Applications:

  WB, ELISA

• Dilution:

  WB: 1/500-1/1000 ELISA: 1/10000

• Purity:

  Affinity Purified

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 52 kDa; Observed MW: 52 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of Smad1/5/9 in 293T lysates using Smad1/5/9 antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4