Prostate Specific Antigen polyclonal antibody

• Background:

  PSA/KLK3 is a member of the glandular kallikrein subfamily of serine proteases. Upon cleavage of 7 amino-terminal amino acids, it is activated to liquefy semen in the seminal coagulum. Although PSA/KLK3 is produced in healthy individuals, investigators have found abnormally high levels in the blood of men with advanced prostate cancer.

• Structure Composition:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

• Product Name Alternative:

  KLK3; APS; Prostate-specific antigen; PSA; Gamma-seminoprotein; Seminin; Kallikrein-3; P-30 antigen; Semenogelase

• Swiss Prot:

  P07288

• Reactivity:

  Human

• Immunogen:

  The antiserum was produced against synthesized peptide derived from the Internal region of human KLK3. AA range:131-180

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC-P, ELISA

• Dilution:

  WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

• Purity:

  Affinity Purified

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 29 kDa; Observed MW: 29 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of Prostate Specific Antigen in NIH3T3 lysates using Prostate Specific Antigen antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4