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CD6 polyclonal antibody

CAT: 0384-NCP0218P-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-NCP0218P-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166.Contributes to signaling cascades triggered by activation of the TCR/CD3 complex.Functions as costimulatory molecule; promotes T-cell activation and proliferation.Contributes to the formation and maturation of the immunological synapse.Functions as calcium-dependent pattern receptor that binds and aggregates both Gram-positive and Gram-negative bacteria. Binds both lipopolysaccharide (LPS) from Gram-negative bacteria and lipoteichoic acid from Gram-positive bacteria.LPS binding leads to the activation of signaling cascades and down-stream MAP kinases.Mediates activation of the inflammatory response and the secretion of pro-inflammatory cytokines in response to LPS.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
T-cell differentiation antigen CD6; T12; TP120; CD6; Soluble CD6
Swiss Prot
P30203
Reactivity
Rat, Mouse, Human
Immunogen
Recombinant protein of human CD6.
Conjugation
Unconjugated
Applications
WB IF
Dilution
WB: 1:1000~1:2000 IF 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 95 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CD6 polyclonal antibody detects endogenous levels of CD6 protein.
Applications Notes
Western blot (WB) analysis of CD6 polyclonal antibody at 1:1000 dilution Lane1:The Heart tissue lysate of Mouse (30ug) Lane2:The Heart tissue lysate of Rat (30ug) Lane3:HuT78 whole cell lysate (6ug)
Host or Source
Rabbit

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