Products for Research Use Only

FoxO3A (P247) polyclonal antibody

CAT: 0384-BS3574-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS3574-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. Forkhead transcription factors of the FoxO subfamily are emerging as a shared component among pathways regulating diverse cellular functions, such as differentiation, metabolism, proliferation, and survival. Their transcriptional output is controlled via a two-tiered mechanism of phosphorylation and acetylation.FOXO3A is a transcriptional activator which triggers apoptosis in the absence of survival factors.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1; FOXO3; FKHRL1; FOXO3A
Swiss Prot
O43524
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 221-270 of Human FoxO3A.
Conjugation
Unconjugated
Related Pathways
Insulin &Glucose Signaling, Cell Cycle Control G1 S Checkpoint
Applications
WB IHC IF IP
Dilution
WB: 1:500~1:2000 IHC: 1:50~1:200 IF: 1:50~1:200 IP: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 80-90 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
FoxO3A (P247) polyclonal antibody detects endogenous levels of FoxO3A protein.
Applications Notes
Western blot (WB) analysis of FoxO3A (P247) polyclonal antibody at 1:1000 dilution Lane1:A549 whole cell lysate (30ug) Lane2:SP2/0 whole cell lysate (30ug) Lane3:C6 whole cell lysate (30ug)
Host or Source
Rabbit