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ADRA1D polyclonal antibody

CAT: 0384-BS61380-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS61380-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
α1D-adrenergicreceptors (α1D-ARs) couple to Gq/11 and participate directly in sympatheticregulation ofsystemic blood pressure byvasoconstriction. α1D-AR can form hetero-oligomers with α1B receptors. α1D-AR transcripts are abundant in prostate and aorta. α1A adrenergicreceptors (α1A-ARs) mediate actionsin the sympathetic nervoussystem through the binding of the catecholamines, epinephrine and norepinephrine. α1A-adrenergic receptors couple to Gq/11 and regulate blood pressure due to changesin vascular tone and cardiac output. Alternative splicing of this gene generatesfour isoforms with distinct C-termini, and the different expression profile of these subtypes produces distinct patterns of activation. α1A-AR transcripts are abundant in heart, brain, liver, and prostate. α1A-AR transcriptsizes of 6.0, 4.0, 3.0, and 2.0 kb have been detected in liver. α1A-AR transcriptsizes of 6.0, 4.0 and 3.0 kb transcripts have been detected in heart, and 6.0 kb and 4.0 kb transcripts have been detected in prostate.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Alpha-1D adrenergic receptor; Alpha-1A adrenergic receptor; Alpha-1D adrenoreceptor; Alpha-1D adrenoceptor; Alpha-adrenergic receptor 1a; ADRA1D; ADRA1A
Swiss Prot
P25100
Reactivity
Human
Immunogen
Synthetic peptide, corresponding to amino acids456-501 of Human ADRA1D
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 60 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ADRA1D polyclonal antibody detects endogenous levels of ADRA1D protein.
Applications Notes
Western blot (WB) analysis of ADRA1D polyclonal antibody at 1:500 dillution Lane1:MCF-7 whole cell lysate (40μg)
Host or Source
Rabbit

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