EBP50 Rabbit monoclonal antibody

• Background:

  Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

• Product Name Alternative:

  SLC9A3R1; EBP50; NPHLOP2; NHERF; NHERF-1; NHERF1

• Swiss Prot:

  O14745

• Reactivity:

  Human Rat

• Immunogen:

  A synthesized peptide derived from human EBP50

• Conjugation:

  Unconjugated

• Applications:

  WB IHC

• Dilution:

  WB 1:500~1:2000 IHC 1:50~1:200

• Purity:

  Affinity-chromatography

• Modification:

  Unmodified

• Molecular Weight:

  50kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  EBP50 Antibody detects endogenous levels of total EBP50

• Applications Notes:

  Western blot analysis of EBP50 expression in (1) HepG2 cell lysate; (2) PC12 cell lysate.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4