PP2A alpha + beta Rabbit monoclonal antibody

• Background:

  Protein phosphatase type 2A (PP2A) is an essential protein serine/threonine phosphatase that is conserved in all eukaryotes. PP2A is a key enzyme within various signal transduction pathways as it regulates fundamental cellular activities such as DNA replication, transcription, translation, metabolism, cell cycle progression, cell division, apoptosis and development. The core enzyme consists of catalytic C and regulatory A (or PR65) subunits, with each subunit represented by α and β isoforms.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

• Product Name Alternative:

  PP2A alpha; PP2A beta; Replication protein C; PPP2CA; PPP2CB

• Swiss Prot:

  P62714/P67775

• Reactivity:

  Human Mouse Rat

• Immunogen:

  A synthesized peptide derived from human alpha + beta PP2A

• Conjugation:

  Unconjugated

• Applications:

  WB IHC ICC/IF IP

• Dilution:

  WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

• Purity:

  Affinity-chromatography

• Modification:

  Unmodified

• Molecular Weight:

  ~ 35 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  PP2A alpha + beta Antibodydetects endogenous levels of total PP2A alpha + beta

• Applications Notes:

  Western blot (WB) analysis of PP2A alpha + beta Rabbit monoclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate (30ug) Lane2:HEK293T whole cell lysate (30ug) Lane3:The Liver tissue lysate of Mouse (30ug) Lane4:The Brain tissue lysate of Rat (30ug)

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4