APOA1 polyclonal antibody

• Background:

  The human apoA-I gene encodes a single chain, 243 amino acid protein which promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in the plasma. It can function as a cofactor for lecithin cholesterolacyltransferase (LCAT), which is responsible for the formation of most plasma cholesteryl esters. The human apoA-II gene encodes the second most abundant protein of HDL particles, where it influences plasma levels of free fatty acids (FFA) . The human apoA-IV gene encodes a 396 amino acid preprotein, which after proteolytic processing is secreted from the intestine in association with chylomicron particles.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  Apo AI; Apo-AI; ApoA I; ApoA-I; APOA1; APOA1/APOC3 fusion gene; APOA1; Apolipoprotein A I precursor; Apolipoprotein A-I (1-242) ; Apolipoprotein A1; Apolipoprotein AI; Apolipoprotein of high density lipoprotein; ApolipoproteinAI; Brp14; Ltw1; Lvtw1; MGC117399; Sep1; Sep2

• Swiss Prot:

  P02647

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein of human APOA1.

• Conjugation:

  Unconjugated

• Related Pathways:

  Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease

• Applications:

  WB

• Dilution:

  WB: 1:500~1:2000

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodified

• Molecular Weight:

  ~ 24 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  APOA1 polyclonal antibody detects endogenous levels of APOA1 protein.

• Applications Notes:

  Western blot (WB) analysis of APOA1 pAb at 1:1000 dilution Lane1:PC12 whole cell lysate (30ug) Lane2:CT-26 whole cell lysate (30ug) Lane3:The Liver tissue lysate of Mouse (30ug) Lane4:HCT116 whole cell lysate (30ug) Lane5:HepG2 whole cell lysate (30ug)

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4