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G3BP1 polyclonal antibody

CAT: 0384-BS8472-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS8472-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
G3BP is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
G3BP1; G3BP; hDH VIII; G3BP-1; Ras GTPase-activating protein-binding protein 1; GAP SH3 domain-binding protein 1
Swiss Prot
Q13283
Reactivity
Human, Mouse, Rat
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human G3BP1.
Conjugation
Unconjugated
Applications
WB, IHC, IF/ICC
Dilution
WB,1:500 - 1:1000|IHC,1:100 - 1:200|IF/ICC,1:100 - 1:500
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 70 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
G3BP1 polyclonal antibody detects endogenous levels of G3BP1 protein.
Applications Notes
Western blot analysis of G3BP1 expression in A375 (A), DLD (B) whole cell lysates.
Host or Source
Rabbit

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