Beta 2 Microglobulin polyclonal antibody

• Background:

  This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  B2M; IMD43

• Swiss Prot:

  P61769

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human beta 2 Microglobulin (NP_004039.1) .

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, IF/ICC

• Dilution:

  WB,1:500 - 1:1000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodified

• Molecular Weight:

  ~ 12 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  Beta 2 Microglobulin polyclonal antibody detects endogenous levels of beta 2 Microglobulin protein.

• Applications Notes:

  Western blot analysis of Beta 2 Microglobulin expression in Jurkat (A), COS7 (B), K562 (C), mouse lung (D), mouse liver (E) whole cell lysates.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4