KEAP1 polyclonal antibody

CAT: 0384-BS6783-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS6783-01Size:50 µL
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Background
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
KEAP1; INrf2; KLHL19
Swiss Prot
Q14145
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human KEAP1 (NP_036421.2) .
Conjugation
Unconjugated
Applications
WB, IHC, IF/ICC
Dilution
WB,1:500 - 1:1000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 60 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
KEAP1 Polyclonal Antibody detects endogenous levels of KEAP1 protein.
Applications Notes
Western blot analysis of KEAP1 expression in mouse brain (A), rat brain (B) whole cell lysates.
Host or Source
Rabbit

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