ASC/TMS1 polyclonal antibody

CAT: 0384-BS79689-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS79689-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD) . The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
PYCARD; ASC; CARD5; TMS; TMS-1; TMS1; PYD and CARD domain containing; ASC / TMS1
Swiss Prot
Q9ULZ3
Reactivity
Human, Mouse, Rat
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ASC.
Conjugation
Unconjugated
Applications
WB, IHC, IF/ICC
Dilution
WB,1:500 - 1:1000|IHC,1:100 - 1:200|IF/ICC,1:100 - 1:500
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 24 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ASC/TMS1 Polyclonal Antibody detects endogenous levels of ASC/TMS1 protein.
Applications Notes
Western blot analysis of ASC expression in HEK293T (A), Raw264.7 (B), mouse brain (C), rat brain (D) whole cell lysates.
Host or Source
Rabbit

Related Products

CatalogName
BS91359TMS1 polyclonal antibody
BZ16341ASC polyclonal antibody
BS2215-01TMS1 (E13) polyclonal antibody
BS2072-01ASC-1 (G105) polyclonal antibody
BS40223-01TMS1 Rabbit monoclonal antibody
PPL00426-2bPEGFP-C3-ASC
PPL01752-2bPmCherry-C1-ASC
PPL00426PCMV-SPORT6-ASC
PPL00426-2aPCMV-Flag-ASC
BS48450TMS1 Recombinant Rabbit mAb

Alternative Products

CatalogName
RD80686A-01ASC / TMS1 Polyclonal Antibody
APR00060GPolyclonal ASC/TMS1 Antibody
bs-41334RASC/TMS1 Polyclonal Antibody
20-1005-50Polyclonal antibody to ASC/TMS1
NBP1-77297Rabbit Polyclonal ASC/TMS1 Antibody
MF-0067007-01Anti-ASC/TMS1 Polyclonal Antibody
AF6234ASC/TMS1 Rabbit Polyclonal Antibody
MBS9439425-01ASC/TMS1 Polyclonal Conjugated Antibody
ANT-10306-50ugASC / TMS1 / PYCARD Polyclonal Antibody
AF6515-01TMS1/ASC Antibody

Popular Products