USP22 polyclonal antibody

• Background:

  Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  USP22; USP3L

• Swiss Prot:

  Q9UPT9

• Reactivity:

  Human, Mouse

• Immunogen:

  A synthetic peptide of human USP22 (NP_056091.1) .

• Conjugation:

  Unconjugated

• Applications:

  WB

• Dilution:

  WB,1:500 - 1:2000

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodified

• Molecular Weight:

  60kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  USP22 Polyclonal Antibody detects endogenous levels of USP22 protein.

• Applications Notes:

  Western blot analysis of USP22 expression in HeLa (A), mouse brain (B) whole cell lysates.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4