USP22 polyclonal antibody

• Background :

  Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.

• Structure Composition :

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative :

  USP22; USP3L

• Swiss Prot :

  Q9UPT9

• Reactivity :

  Human, Mouse

• Immunogen :

  A synthetic peptide of human USP22 (NP_056091.1) .

• Conjugation :

  Unconjugated

• Applications :

  WB

• Dilution :

  WB,1:500 - 1:2000

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodified

• Molecular Weight :

  60kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  USP22 Polyclonal Antibody detects endogenous levels of USP22 protein.

• Applications Notes :

  Western blot analysis of USP22 expression in HeLa (A), mouse brain (B) whole cell lysates.

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4