COL2A1 polyclonal antibody

CAT: 0384-BS80235-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS80235-01Size:50 µL
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Background
This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
COL2A1; ANFH; AOM; COL11A3; SEDC; STL1
Swiss Prot
P02458
Reactivity
Human, Mouse, Rat
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human COL2A1.
Conjugation
Unconjugated
Applications
WB, IHC
Dilution
WB,1:500 - 1:1000|IHC,1:100 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 220 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
COL2A1 polyclonal antibody detects endogenous levels of COL2A1 protein.
Applications Notes
Western blot analysis of COL2A1 expression in Panc1 (A) whole cell lysates.
Host or Source
Rabbit

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