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ACE (F940) polyclonal antibody

CAT: 0384-BS3485-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS3485-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Angiotensin-converting enzyme (ACE) is a carboxy-terminal dipeptidyl exo-peptidase that converts Angiotensin I to the potent vasopressive hormone, Angiotensin II. There are two isoforms of ACE, the pulmonary ACEP and the testicular ACET. ACEP is a glycoprotein expressed in vascular endothelial cells of the lung, liver, adrenal cortex, pancreas, kidney and spleen. The ACET isoform is expressed exclusively in adult testis by developing sperm cells, specifically, late pachytene spermatocytes. Additionally, ACE inactivates bradykinin, a vasodepressor peptide, and is involved in fluid/electrolyte homeostasis.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Angiotensin-converting enzyme; Short name=ACE; Dipeptidyl carboxypeptidase I; CD143; ACE1; DCP; DCP1; Angiotensin Converting Enzyme 1
Swiss Prot
P12821
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 920-950 of Human ACE.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 170 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ACE (F940) polyclonal antibody detects endogenous levels of Angiotensin-converting enzyme protein.
Applications Notes
Western blot (WB) analysis of ACE (F940) pAb at 1:500 dilution Lane1:PC3 whole cell lysate (40ug) Lane2:A549 whole cell lysate (40ug) Lane3:SGC7901 whole cell lysate (40ug)
Host or Source
Rabbit

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