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Nup160 (L424) polyclonal antibody

CAT: 0384-BS3355-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS3355-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Nuclear pore complexes (NPCs) are the channels for the bi-directional movement of macromolecules between the nucleus and cytoplasm, and contain more than 100 different subunits. Many of them belong to a family called nucleoporins, which are characterized by the presence of O-linked N-acetylglucosamine moieties and a distinctive pentapeptide repeat (XFXFG) .Nuclear pore complex protein Nup96 (Nup96) is formed by cleavage of a 186 kDa precursor protein. This proteolytic cleavage yields two nucleoporins, Nup98 and Nup96. Nup96 is part of the Nup160 subcomplex in the nuclear pore (which consists of Nup160, Nup133, Nup107 and Nup96) . Nup96 plays a major role in the two-way transport across the nuclear pore and is important in RNA export.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Nuclear pore complex protein Nup160; 160 kDa nucleoporin; Nucleoporin Nup160; NUP160; KIAA0197; NUP120
Swiss Prot
Q12769
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 400-450 of Human Nup160.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~160 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Nup160 (L424) polyclonal antibody detects endogenous levels of Nup160 protein.
Applications Notes
Western blot (WB) analysis of Nup160 (L424) pAb at 1:2000 dilution Lane1:Hela whole cell lysate (20ug) Lane2:K562 whole cell lysate (20ug) Lane3:The Testis tissue lysate of Mouse (40ug) Lane4:The Uterus tissue lysate of Rat (40ug)
Host or Source
Rabbit

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