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CaMKV (N217) polyclonal antibody

CAT: 0384-BS2493-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS2493-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The Ca2+/calmodulin-dependent protein kinases (CaMKs) comprise a structurally related subfamily of serine/threonine kinases. CAMKV (CaM kinaselike vesicle-associated), also known as 1G5 or VACAMKL, is a 501 amino acid protein that localizes to cytoplasmic vesicles, as well as to the cell membrane, and contains one protein kinase domain. Although a member of the CaMK family, CaMKV is thought to be catalytically inactive, but it may play a role in vesicle function and nervous system development. Multiple isoforms of CaMKV exist due to alternative splicing events. The gene encoding CaMKV maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and CharcotMarie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
CaM kinase-like vesicle-associated protein; CAMKV
Swiss Prot
Q8NCB2
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 186-247 of Human CaMKV.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:1000~1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 54 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CaMKV (N217) polyclonal antibody detects endogenous levels of CaMKV protein.
Applications Notes
Western blot (WB) analysis of CaMKV (N217) polyclonal antibody at 1:1000 dilution Lane1:HEK293T whole cell lysate (40ug) Lane2:U-87MG whole cell lysate (40ug) Lane3:PC12 whole cell lysate (40ug) Lane4:BV2 whole cell lysate (40ug)
Host or Source
Rabbit

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