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MX2 polyclonal antibody

CAT: 0384-BS5805-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS5805-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Members of the Dynamin family include GTPase, microtubule-associated proteins that are involved in cellular trafficking, including microtubule bundling and endocytosis. Mx1, also known as MxA, an interferon (IFN) -induced protein, acquires a high degree of resistance to influenza A virus and the rhabdo-virus vesicular stomatitis virus (VSV), which suggests that Mx1 plays an active role against influenza virus and the rhabdovirus VSV. Mx1 is a cytoplasmic protein that is 63% identical to the Mx2 protein, which lacks antiviral activity. Mx2 is also known as MxB and is localized at the cytoplasmic face of nuclear pores. Mx2 expression is not interferon-dependent and this protein is thought to regulate the efficiency and/or kinetics of nuclear import, a function which may have been usurped by its antiviral relatives.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Interferon-induced GTP-binding protein Mx2; Interferon-regulated resistance GTP-binding; protein MxB; Myxovirus resistance protein 2; p78-related protein
Swiss Prot
P20592
Reactivity
Human
Immunogen
Recombinant full length Human MX2.
Conjugation
Unconjugated
Applications
WB IF IP
Dilution
WB: 1:1000~1:2000 IF: 1:50~1:200 IP: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 85 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
MX2 polyclonal antibody detects endogenous levels of MX2 protein.
Applications Notes
Western blot (WB) analysis of MX2 polyclonal antibody at 1:1000 dilution Lane1:A431 cell lysate (30ug) Lane2:Jurkat cell lysate (30ug) Lane3:HepG2 cell lysate (30ug) Lane4:THP-1 cell lysate (30ug)
Host or Source
Rabbit

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