EpCAM polyclonal antibody

• Background :

  This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.

• CAS Number :

  9007-83-4

• Structure Composition :

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative :

  EPCAM; DIAR5; EGP-2; EGP314; EGP40; ESA; HNPCC8; KS1/4; KSA; M4S1; MIC18; MK-1; TACSTD1; TROP1

• Swiss Prot :

  P16422

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  KLH-conjugated synthetic peptide encompassing a sequence within the center region of human EpCAM.

• Conjugation :

  Unconjugated

• Applications :

  WB, IF/ICC

• Dilution :

  WB,1:500 - 1:1000|IF/ICC,1:50 - 1:200

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodified

• Molecular Weight :

  ~ 40 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  EpCAM polyclonal antibody detects endogenous levels of EpCAM protein.

• Applications Notes :

  Western blot analysis of EpCAM expression in HCT116 (A), CT26 (B), PC12 (C) whole cell lysates.

• Host or Source :

  Rabbit