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BCATc Inhibitor 2

CAT: 0804-HY-116044-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-116044-01Size:5 mg
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Description
BCATc Inhibitor 2 is a selective branched-chain aminotransferase (BCAT) inhibitor for research of neurodegenerative diseases. The IC50s of 0.2 μM, 0.8 μM and 3.0 μM for rat cytosolic isoenzyme rBCATc, human cytosolic isoenzyme hBCATc and rat mitochondrial isoenzyme rBCATm, respectively. BCATc, also called BCAT1, is in the cytoplasm[1].
CAS Number
406191-34-2
Product Name Alternative
(+)-MCPG
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Aminotransferases (Transaminases)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bcatc-inhibitor-2.html
Concentration
10mM
Purity
99.28
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
ClC1=CC=C2C(C=C(O2)C(NNS(C3=C(C=CC=C3)C(F)(F)F)(=O)=O)=O)=C1
Molecular Formula
C16H10ClF3N2O4S
Molecular Weight
418.77
Precautions
H315, H319
References & Citations
[1]Lain-Yen Hu, et al. The Design and Synthesis of Human Branched-Chain Amino Acid Aminotransferase Inhibitors for Treatment of Neurodegenerative Diseases. Bioorg Med Chem Lett. 2006 May 1;16 (9) :2337-40.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

CatalogName
BUP03661-01BCATc Inhibitor 2
MBS6408245-01BCAT1 (Branched-chain-amino-acid Aminotransferase,, BCT1, PP18, BCATC, ECA39, MECA39, PNAS121) (MaxLight 750)
MBS6408242-01BCAT1 (Branched-chain-amino-acid Aminotransferase,, BCT1, PP18, BCATC, ECA39, MECA39, PNAS121) (MaxLight 490)
209727-01BCAT1 (Branched-chain-amino-acid Aminotransferase, , BCT1, PP18, BCATC, ECA39, MECA39, PNAS121) discontinued
MBS6408246-01BCAT1 (Branched-chain-amino-acid Aminotransferase,, BCT1, PP18, BCATC, ECA39, MECA39, PNAS121) (PE)
MBS6408240-01BCAT1 (Branched-chain-amino-acid Aminotransferase,, BCT1, PP18, BCATC, ECA39, MECA39, PNAS121) (HRP)
MBS6408238-01BCAT1 (Branched-chain-amino-acid Aminotransferase,, BCT1, PP18, BCATC, ECA39, MECA39, PNAS121) (Biotin)
MBS6408237-01BCAT1 (Branched-chain-amino-acid Aminotransferase,, BCT1, PP18, BCATC, ECA39, MECA39, PNAS121) (APC)
MBS6408236-01BCAT1 (Branched-chain-amino-acid Aminotransferase,, BCT1, PP18, BCATC, ECA39, MECA39, PNAS121) (AP)
MBS6408239-01BCAT1 (Branched-chain-amino-acid Aminotransferase,, BCT1, PP18, BCATC, ECA39, MECA39, PNAS121) (FITC)

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