Products for Research Use Only
RegisterLogin

A-70874

CAT: 0804-HY-129516Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-129516Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
A-70874 is a tyrosine-free tetrapeptide analog of cholecystokinin (30-33) (CCK-4) . A-70874 is an agonist that stimulates pancreatic amylase release and a partial agonist that stimulates pancreatic phosphoinositide decomposition. A-70874 has an IC50 of 4.9 nM for the guinea pig pancreatic CCK receptor. Cholecystokinin (CCK) receptors are divided into CCK-A (digestive tract) and CCK-B (brain) . A-70874 has an affinity of 1.6 μM for the CCK-B/gastrin receptor[1].
CAS Number
131449-37-1
UNSPSC
12352005
Target
Cholecystokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/a-70874.html
Smiles
NC([C@H](CC1=CC=CC=C1)N(C)C([C@H](CC(O)=O)NC([C@H](CCCCNC(/C=C/C2=CC=C(O)C=C2)=O)NC([C@@H](NC(OC(C)(C)C)=O)CC3=CNC4=C3C=CC=C4)=O)=O)=O)=O
Molecular Formula
C45H55N7O10
Molecular Weight
853.96
References & Citations
[1]Lin CW, et al. Characterization of two novel cholecystokinin tetrapeptide (30-33) analogues, A-71623 and A-70874, that exhibit high potency and selectivity for cholecystokinin-A receptors. Mol Pharmacol. 1991 Mar;39 (3) :346-51.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-RI03914-01Mmu-miR-7084-5p inhibitor
HY-RI03920A-01Mmu-miR-7087-5p antagomir
HY-R03914-01Mmu-miR-7084-5p mimic
HY-R03920-01Mmu-miR-7087-5p mimic
HY-R03913A-01Mmu-miR-7084-3p agomir
HY-R03914A-01Mmu-miR-7084-5p agomir
HY-R03919-01Mmu-miR-7087-3p mimic
HY-R03920A-01Mmu-miR-7087-5p agomir
HY-R03913-01Mmu-miR-7084-3p mimic
HY-RI03914A-01Mmu-miR-7084-5p antagomir

Alternative Products

CatalogName
MBS5779136A 70874

Popular Products