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DUSP6 [SR39-09] Antibody

CAT: 1071-OM637046-01Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1071-OM637046-01Size:100 µL
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Description
Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2, hVH-3 (B23), hVH-5, MKP-3, MKP-X, and MKP-4. Human MKP-3 maps to chromosome 12q22-q23 and encodes a 381 amino acid protein that specifically inactivates members of the ERK family and is expressed in a variety of tissues with the highest levels in heart and pancreas.
CAS Number
9007-83-4
Immunogen
Recombinant protein
Antibody Type
Primary Antibodies
Product Name Synonym
Dual specificity phosphatase 6 antibody Dual specificity phosphatase 6 isoform a antibody Dual specificity protein phosphatase 6 antibody Dual specificity protein phosphatase PYST1 antibody DUS6_HUMAN antibody DUSP 6 antibody DUSP 6a antibody Dusp6 antibody DUSP6a antibody HH19 antibody MAP kinase phosphatase 3 antibody Mitogen activated protein kinase phosphatase 3 antibody Mitogen-activated protein kinase phosphatase 3 antibody MKP 3 antibody MKP-3 antibody MKP3 antibody PYST 1 antibody PYST1 antibody Serine/threonine specific protein phosphatase antibody