DL-α-Tocopherol acetate-13C4,d6

DL-α-Tocopherol acetate-13C4,d6

• UNSPSC Description: DL-α-Tocopherol acetate-13C4,d6 is the deuterium and 13C labeled DL-α-Tocopherol acetate[1]. DL-α-Tocopherol acetate is a vitamin E derivative which is often included in the formulations of enteral nutrition[2][3].
• Target Antigen: Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Others
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Solubility: 10 mM in DMSO
• Smiles: CC1=C2C(CC[C@](O2)(CCC[C@@H](CCC[C@@H](CCCC(C)C)C)C)C)=C([13C]([2H])([2H])[2H])C(O[13C]([13CH3])=O)=C1[13C]([2H])([2H])[2H]
• Molecular Weight: 482.75
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Nagy K, et al. Double-balloon jejunal perfusion to compare absorption of vitamin E and vitamin E acetate in healthy volunteers under maldigestion conditions. Eur J Clin Nutr. 2013 Feb;67(2):202-6.|[3]Nishio K, et al. α-Tocopheryl phosphate: uptake, hydrolysis, and antioxidant action in cultured cells and mouse. Free Radic Biol Med. 2011 Jun 1550(12):1794-800.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported