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Metaproterenol

CAT: 0804-HY-B1276ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-B1276ASize:1 Each
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Description
Metaproterenol (Orciprenaline) is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist with an IC50 of 68 nM. Metaproterenol also has anti-inflammatory activity[1][2].
CAS Number
586-06-1
Product Name Alternative
Orciprenaline
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Inflammation/Immunology; Cardiovascular Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/metaproterenol.html
Solubility
10 mM in DMSO
Smiles
OC1=CC(C(O)CNC(C)C)=CC(O)=C1
Molecular Formula
C11H17NO3
Molecular Weight
211.26
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Noh H, et al. Beta 2-adrenergic receptor agonists are novel regulators of macrophage activation in diabetic renal and cardiovascular complications. Kidney Int. 2017 Jul;92 (1) :101-113.|[2]Ibrahim FA, et al. Highly sensitive spectrofluorimetric method for rapid determination of orciprenaline in biological fluids and pharmaceuticals. Luminescence. 2019 Feb;34 (1) :77-83.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β adrenergic receptor

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