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Levobunolol

CAT: 0804-HY-B1035ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-B1035ASize:1 Each
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Description
Levobunolol (l-Bunolol) is a potent and nonselective β-adrenergic receptor antagonist. Levobunolol is an ocular hypotensive agent and lowers mean intraocular pressure (IOP) . Levobunolol can be used for glaucoma and superior oblique myokymia (SOM) research[1][2][3].
CAS Number
47141-42-4
Product Name Alternative
L-Bunolol
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/levobunolol.html
Solubility
10 mM in DMSO
Smiles
O=C1CCCC2=C1C=CC=C2OC[C@@H](O)CNC(C)(C)C
Molecular Formula
C17H25NO3
Molecular Weight
291.39
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Mohammadi M, et al. Injectable drug depot engineered to release multiple ophthalmic therapeutic agents with precise time profiles for postoperative treatment following ocular surgery. Acta Biomater. 2018 Jun;73:90-102.|[2]Kumar, N, et al. Extended levobunolol release from Eudragit nanoparticle-laden contact lenses for glaucoma therapy. Futur J Pharm Sci 6, 109 (2020) .|[3]Zhang M, et al. Superior oblique myokymia treated with levobunolol. J AAPOS. 2018 Feb;22 (1) :67-69.e2.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β adrenergic receptor

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