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Mangafodipir

CAT: 0804-HY-B0993ASize: 1 EachDry Ice: NoHazardous: No
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Description
Mangafodipir, hepatocellular-specific contrast agent, is an efficacious inhibitor of CIPN (chemotherapy-induced peripheral neuropath) and other conditions caused by cellular oxidative stress. Mangafodipir shows no negative interference with the tumoricidal activity of chemotherapy[1][2].
CAS Number
155319-91-8
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mangafodipir.html
Solubility
10 mM in DMSO
Smiles
O=C1[O-][Mn+2]([N]2(C3)CC4=C5COP([O-])([O-])=O)([O-]C6=C(N=C7)C)([O-]C4=C(N=C5)C)([O-]C3=O)[N](CC6=C7COP([O-])([O-])=O)(CC2)C1.[H+].[H+].[H+].[H+].[H+].[H+]
Molecular Formula
C22H30MnN4O14P2
Molecular Weight
691.38
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Karlsson JOG, et al. Mangafodipir a Selective Cytoprotectant - with Special Reference to Oxaliplatin and Its Association to Chemotherapy-Induced Peripheral Neuropathy (CIPN) . Transl Oncol. 2017 Aug;10 (4) :641-649. |[2]Wang C. Mangafodipir trisodium (MnDPDP) -enhanced magnetic resonance imaging of the liver and pancreas. Acta Radiol Suppl. 1998;415:1-31.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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