Products for Research Use Only
RegisterLogin

Buprofezin-d6

CAT: 0804-HY-B0831SSize: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B0831SSize:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Buprofezin-d6 is the deuterium labeled Buprofezin. Buprofezin is a broad-spectrum insecticide and chitin synthesis inhibitor that targets developmental stage coleopteran pests.Buprofezin promotes the conversion of energy metabolism from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Buprofezin also promotes the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase[1][2].
CAS Number
2140803-94-5
UNSPSC
12352005
Target
Oxidative Phosphorylation; Reactive Oxygen Species (ROS)
Type
Isotope-Labeled Compounds
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Solubility
10 mM in DMSO
Smiles
[2H]C([2H])([2H])C(N1/C(SCN(C2=CC=CC=C2)C1=O)=N/C(C)(C)C)C([2H])([2H])[2H]
Molecular Formula
C16H17D6N3OS
Molecular Weight
311.48
References & Citations
[1]Ji X, et al. Potential hepatic toxicity of buprofezin at sublethal concentrations: ROS-mediated conversion of energy metabolism. J Hazard Mater. 2016 Dec 15;320:176-186. |[2]YoshioIzawa, et al. Inhibition of chitin biosynthesis by buprofezin analogs in relation to their activity controlling Nilaparvata lugens Stål. Pestic Biochem Physiol, 1985, 24 (3) : 343-347.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-223.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-B0831-01Buprofezin
HY-B0831RBuprofezin (Standard)
HY-110225-01Levetiracetam-d6 (ring-d6)
HY-N0893STetrahydrocurcumin-d6
HY-W750155Tetramethrin-d6
HY-W744578Taurolidine-d6
HY-W744275Tipelukast-d6
HY-W704964-01Dimethylcyanamide-d6
HY-W010201SCitronellol-d6
HY-N0709S1Coumarin-d6

Alternative Products

CatalogName
BA6209-100Buprofezin
RG-A260867-01(Ez) -Buprofezin
TRC-B689672-100MGBuprofezin-d7
P15330ABuprofezin [CAS:69327-76-0] 100ug/ml in Acetone
CS-O-59102Fruquintinib-d6 (Dimethoxy-d6)
UYB80274-01Bezafibrate-d6 (dimethyl-d6)
TMIJ-0459-01Methamidophos-d6 (dimethyl-d6)
RM-P052032-01Pentoxifylline-D6 (Dimethyl-D6)
TRC-M260801-5MGMethoxychlor-d6 (dimethoxy-d6)
AR-T06190-01Tucatinib-d6 (Irbinitinib-d6)

Popular Products