Ceftibuten (monohydrate)

• Description :

  Ceftibuten (Sch39720) monohydrate, an antibiotic, is an orally active cephalosporin, possesses potent activity in vitro against a wide range of gram-negative and certain gram-positive pathogens[1][2].

• Product Name Alternative :

  Sch 39720 (monohydrate)

• UNSPSC :

  12352005

• Target :

  Antibiotic; Bacterial; Beta-lactamase

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/ceftibuten-hydrate.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C(N12)=CCS[C@]2([H])[C@H](NC(/C(C3=CSC(N)=N3)=C\CC(O)=O)=O)C1=O)O.O

• Molecular Formula :

  C15H16N4O7S2

• Molecular Weight :

  428.44

• References & Citations :

  [1]Shawar R, et al. Comparative in vitro activity of ceftibuten (Sch 39720) against bacterial enteropathogens. Antimicrob Agents Chemother. 1989;33 (5) :781-784.|[2]Kearns GL, et al. Single-dose pharmacokinetics of ceftibuten (SCH 39720) in infants and children. Antimicrob Agents Chemother. 1991;35 (10) :2078-2084.|[3]Tamai I, et al. Functional expression of intestinal dipeptide/beta-lactam antibiotic transporter in Xenopus laevis oocytes. Biochem Pharmacol. 1994;48 (5) :881-888.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• Isoform :

  β-lactam

• CAS Number :

  [1346153-47-6]