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Cefepime (chloride)

CAT: 0804-HY-B0692ASize: 1 EachDry Ice: NoHazardous: No
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Description
Cefepime (BMY-28142) chloride is a broad-spectrum and cross the blood-brain barrier cephalosporin. Cefepime chloride shows antibacterial effects against both Gram-positive and Gram-negative aerobic bacteria. Cefepime chloride induces neurotoxicity[1][2][3][4].
CAS Number
107648-79-3
Product Name Alternative
BMY-28142 (chloride)
UNSPSC
12352005
Target
Antibiotic; Bacterial; Penicillin-binding protein (PBP)
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/cefepime-chloride.html
Solubility
10 mM in DMSO
Smiles
C[N+]1(CC(CS[C@]2([H])[C@@H]3NC(/C(C4=CSC(N)=N4)=N\OC)=O)=C(C(O)=O)N2C3=O)CCCC1.[Cl-]
Molecular Formula
C19H25ClN6O5S2
Molecular Weight
517.02
References & Citations
[1]Yahav D, et al. Efficacy and safety of cefepime: a systematic review and meta-analysis. Lancet Infect Dis. 2007 May;7 (5) :338-48. |[2]Barradell LB, Bryson HM. Cefepime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1994;47 (3) :471-505.|[3]Payne LE, et al. Cefepime-induced neurotoxicity: a systematic review. Crit Care. 2017 Nov 14;21 (1) :276. doi: 10.1186/s13054-017-1856-1. |[4]Máthé A, et al. The effect of different doses of cisplatin on the pharmacokinetic parameters of cefepime in mice. Lab Anim. 2006 Jul;40 (3) :296-300.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β-lactam