Ciclesonide-d7

• UNSPSC Description:

  Ciclesonide-d7 is the deuterium labeled Ciclesonide. Ciclesonide (RPR251526) is a glucocorticoid with an potent anti-inflammatory activity. Ciclesonide can be used for asthma research[1].

• Target Antigen:

  Glucocorticoid Receptor; Isotope-Labeled Compounds

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Immunology/Inflammation;Others;Vitamin D Related/Nuclear Receptor

• Field of Research:

  Inflammation/Immunology; Endocrinology

• Purity:

  99.99

• Solubility:

  10 mM in DMSO

• Smiles:

  [2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])C(OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5(C(CC4)=CC(C=C5)=O)C)([H])[C@H](C3)O)([H])C[C@@]1([H])O[C@](C6CCCCC6)([H])O2)C)=O)=O

• Molecular Weight:

  547.73

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Mutch, E., et al., The role of esterases in the metabolism of ciclesonide to desisobutyryl-ciclesonide in human tissue. Biochem Pharmacol, 2007. 73(10): p. 1657-64.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1225382-70-6