Deferiprone-d3

• Description:

  Deferiprone-d3 is the deuterium labeled Deferiprone. Deferiprone is the only orally active iron-chelating agent to be used therapeutically in conditions of transfusional iron overload[1][2].

• UNSPSC:

  12352005

• Hazard Statement:

  H302+H312+H332, H315, H319

• Target:

  Ferroptosis; HCV; Isotope-Labeled Compounds

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Anti-infection; Apoptosis; Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cardiovascular Disease; Cancer

• Purity:

  99.46

• Solubility:

  10 mM in DMSO

• Smiles:

  OC1=C(C)N(C([2H])([2H])[2H])C=CC1=O

• Molecular Formula:

  C7H6D3NO2

• Molecular Weight:

  142.17

• Precautions:

  H302+H312+H332, H315, H319

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Kontoghiorghes GJ, et al. Benefits and risks of deferiprone in iron overload in Thalassaemia and other conditions: comparison of epidemiological and therapeutic aspects with deferoxamine. Drug Saf. 2003;26 (8) :553-584.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  [1346601-82-8]