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Benztropine

CAT: 0804-HY-B0520-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0520-01Size:5 mg
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Description
Benztropine (Benzatropine; Benzotropine) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research[1]. Benztropine is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine is also a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects[2].
CAS Number
86-13-5
Product Name Alternative
Benzatropine; Benzotropine
UNSPSC
12352005
Target
Dopamine Receptor; Histamine Receptor; mAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/benztropine.html
Purity
98.1200
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CN1[C@H]2CC(OC(C3=CC=CC=C3)C4=CC=CC=C4)C[C@@H]1CC2
Molecular Formula
C21H25NO
Molecular Weight
307.43
References & Citations
[1]Santosh S Kulkarni, et al. Comparative structure-activity relationships of benztropine analogues at the dopamine transporter and histamine H (1) receptors. Bioorg Med Chem. 2006 Jun 1;14 (11) :3625-34.|[2]Jihong Cui, et al. New use of an old drug: inhibition of breast cancer stem cells by benztropine mesylate. Oncotarget. 2017 Jan 3;8 (1) :1007-1022.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
D2 Receptor

Alternative Products

CatalogName
B1554-1000Benztropine mesylate
ALX-550-143-G001Benztropine . mesylate
AR-B06820-01Benztropine HBr
AR-B01392-01Benztropine-d5

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