Rebamipide-d4

• Description :

  Rebamipide-d4 is deuterium labeled Rebamipide. Rebamipide is a mucoprotective agent. Rebamipide induces COX-2 expression, increases PGE2 levels, and enhances gastric mucosal defense in a COX-2-dependent manner[1].

• Product Name Alternative :

  OPC12759-d4; Proamipide-d4

• UNSPSC :

  12352005

• Hazard Statement :

  H301, H312, H330, H410

• Target :

  COX; Isotope-Labeled Compounds; Prostaglandin Receptor

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  GPCR/G Protein; Immunology/Inflammation; Others

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Inflammation/Immunology

• Purity :

  99.0

• Solubility :

  10 mM in DMSO

• Smiles :

  OC(C(NC(C1=C([2H])C([2H])=C(Cl)C([2H])=C1[2H])=O)CC(C2=CC=CC=C2N3)=CC3=O)=O

• Molecular Formula :

  C19H11D4ClN2O4

• Molecular Weight :

  374.81

• Precautions :

  H301, H312, H330, H410

• References & Citations :

  [1]Sun WH, et al. Induction of cyclooxygenase-2 in rat gastric mucosa by rebamipide, a mucoprotective agent. J Pharmacol Exp Ther. 2000 Nov;295 (2) :447-52.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported

• Isoform :

  EP

• CAS Number :

  [1219409-06-9]