Cytidine-d2

• Description:

  Cytidine-d2 is the deuterium labeled Cytidine. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[1][2][3].

• Product Name Alternative:

  Cytosine β-D-riboside-d2; Cytosine-1-β-D-ribofuranoside-d2

• UNSPSC:

  12352005

• Target:

  Endogenous Metabolite; Nucleoside Antimetabolite/Analog

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

• Field of Research:

  Neurological Disease

• Purity:

  99.86

• Solubility:

  10 mM in DMSO|DMSO : 50mg/mL (ultrasonic) |H2O : ≥ 50mg/mL

• Smiles:

  OC[C@@H]1[C@@H] (O) [C@@H] (O) [C@H] (N2C (N=C (N) C ([2H]) =C2[2H]) =O) O1

• Molecular Formula:

  C9H11D2N3O5

• Molecular Weight:

  245.23

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Machado-Vieira R, et, al. New therapeutic targets for mood disorders. ScientificWorldJournal. 2010 Apr 13;10:713-26.|[3]Jonas DA, et al. Safety considerations of DNA in food. Ann Nutr Metab. 2001;45 (6) :235-54.|[4]Wurtman RJ, et al. Effect of oral CDP-choline on plasma choline and uridine levels in humans. Biochem Pharmacol. 2000 Oct 1;60 (7) :989-92.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  40632-25-5