Adenine-15N5

Adenine-15N5

• UNSPSC Description: Adenine-15N5 (6-Aminopurine-15N5; Vitamin B4-15N5) is 15N labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.
• Target Antigen: DNA/RNA Synthesis; Endogenous Metabolite; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Others
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/adenine-15n5.html
• Solubility: 10 mM in DMSO
• Smiles: [15NH2]C1=[15N]C=[15N]C2=C1[15N]=C[15NH]2
• Molecular Weight: 140.09
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]ORO J, et al. Synthesis of purines under possible primitive earth conditions. I. Adenine from hydrogen cyanide. Arch Biochem Biophys. 1961 Aug;94:217-27.|[3]Griffiths AJF, et al. An Introduction to Genetic Analysis. 7th edition. New York: W. H. Freeman; 2000. Structure of DNA.|[4]Reader V. The assay of vitamin B(4). Biochem J. 1930;24(6):1827-31.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported