Products for Research Use Only
RegisterLogin

Sumatriptan (succinate) (Standard)

CAT: 0804-HY-B0121R-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B0121R-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Sumatriptan (succinate) (Standard) is the analytical standard of Sumatriptan (succinate) . This product is intended for research and analytical applications. Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for migraine headache research[1][2].
CAS Number
103628-48-4
Product Name Alternative
GR 43175 succinate (Standard)
UNSPSC
12352005
Target
5-HT Receptor; Reference Standards
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sumatriptan-succinate-standard.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CCC(O)=O.O=S(CC1=CC2=C(NC=C2CCN(C)C)C=C1)(NC)=O
Molecular Formula
C18H27N3O6S
Molecular Weight
413.49
References & Citations
[1]Razzaque Z, et al. Vasoconstriction in human isolated middle meningeal arteries: determining the contribution of 5-HT1B- and 5-HT1F-receptor activation. Br J Clin Pharmacol. 1999 Jan;47 (1) :75-82.|[2]S J Peroutka, et al. Sumatriptan (GR 43175) interacts selectively with 5-HT1B and 5-HT1D binding sites. Eur J Pharmacol. 1989 Apr 12;163 (1) :133-6. |[3]Bates EA, et al. Sumatriptan alleviates nitroglycerin-induced mechanical and thermal allodynia in mice. Cephalalgia. 2010 Feb;30 (2) :170-8.|[4]K L Dechant, et al. Sumatriptan. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the acute treatment of migraine and cluster headache. Drugs. 1992 May;43 (5) :776-98.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Clinical Information
Launched
Isoform
5-HT1 Receptor

Related Products

CatalogName
HY-B0121-01Sumatriptan succinate
HY-B0121BS-01Sumatriptan-d6 (succinate)
HY-B0121BR-01Sumatriptan (Standard)
HY-15777BR-01Ribociclib succinate (Standard)
HY-135815AR-01Mobocertinib (succinate) (Standard)
HY-111529AR-01Tafenoquine (Succinate) (Standard)
HY-15408AR-01Trelagliptin (succinate) (Standard)
HY-W015410R-01Disodium succinate (Standard)
HY-17390AR-01Loxapine (succinate) (Standard)
HY-17503AR-01Metoprolol (succinate) (Standard)

Alternative Products

CatalogName
RM-S132000-01Sumatriptan Succinate

Popular Products