Gestodene-d6

• Description:

  Gestodene-d6is the deuterium labeled Gestodene. Gestodene (SHB 331) is a progestogen hormonal contraceptive[1][2]. Gestodene-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• Product Name Alternative:

  SHB 331-d6; WL 70-d6

• UNSPSC:

  12352211

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  Isotope-Labeled Compounds; Progesterone Receptor

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Others; Vitamin D Related/Nuclear Receptor

• Field of Research:

  Endocrinology

• Solubility:

  10 mM in DMSO

• Smiles:

  CC[C@@]12[C@](C=C[C@@]2(O)C#C)([H])[C@@]3([H])[C@]([C@]4([2H])C(C([2H])([2H])C3)=C([2H])C(C([2H])([2H])C4)=O)([H])CC1

• Molecular Formula:

  C21H20D6O2

• Molecular Weight:

  316.47

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Spona, J. and J. Huber, Pharmacological and endocrine profiles of gestodene. Int J Fertil, 1987. 32 Suppl: p. 6-14.; Pollow, K., et al., Lack of binding of gestodene to estrogen receptor in human breast cancer tissue. Eur J Cancer, 1990. 26 (5) : p. 608-10.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  1542211-40-4