Edaravone-d5

• Description:

  Edaravone-d5 is a deuterium labeled Edaravone. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator[1][2][3][4].

• Product Name Alternative:

  MCI-186-d5

• UNSPSC:

  12352005

• Target:

  Apoptosis; Isotope-Labeled Compounds; MMP

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Apoptosis; Metabolic Enzyme/Protease; Others

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Purity:

  99.52

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1N (C2=C ([2H]) C ([2H]) =C ([2H]) C ([2H]) =C2[2H]) N=C (C) C1

• Molecular Formula:

  C10H5D5N2O

• Molecular Weight:

  179.23

• References & Citations:

  [1]Yoshida, H., et al. Neuroprotective effects of edaravone: a novel free radical scavenger in cerebrovascular injury. CNS Drug Rev, 2006. 12 (1) : p. 9-20.|[2]Okamura, K., et al. Edaravone, a free radical scavenger, attenuates cerebral infarction and hemorrhagic infarction in rats with hyperglycemia. Neurol Res, 2013.|[3]Garcia CA, et al. Edaravone reduces astrogliosis and apoptosis in young rats with kaolin-induced hydrocephalus. Childs Nerv Syst. 2016 Dec 17. [Epub ahead of print]|[4]Bai X, et al. Protective Effect of Edaravone on Glutamate-Induced Neurotoxicity in Spiral Ganglion Neurons. Neural Plast. 2016;2016:4034218. Epub 2016 Nov 10.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  1228765-67-0