Edaravone-d5

• Description :

  Edaravone-d5 is a deuterium labeled Edaravone. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator[1][2][3][4].

• Product Name Alternative :

  MCI-186-d5

• UNSPSC :

  12352005

• Target :

  Apoptosis; Isotope-Labeled Compounds; MMP

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Apoptosis; Metabolic Enzyme/Protease; Others

• Applications :

  Neuroscience-Neurodegeneration

• Field of Research :

  Neurological Disease

• Purity :

  99.52

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1N(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])N=C(C)C1

• Molecular Formula :

  C10H5D5N2O

• Molecular Weight :

  179.23

• References & Citations :

  [1]Yoshida, H., et al. Neuroprotective effects of edaravone: a novel free radical scavenger in cerebrovascular injury. CNS Drug Rev, 2006. 12 (1) : p. 9-20.|[2]Okamura, K., et al. Edaravone, a free radical scavenger, attenuates cerebral infarction and hemorrhagic infarction in rats with hyperglycemia. Neurol Res, 2013.|[3]Garcia CA, et al. Edaravone reduces astrogliosis and apoptosis in young rats with kaolin-induced hydrocephalus. Childs Nerv Syst. 2016 Dec 17. [Epub ahead of print]|[4]Bai X, et al. Protective Effect of Edaravone on Glutamate-Induced Neurotoxicity in Spiral Ganglion Neurons. Neural Plast. 2016;2016:4034218. Epub 2016 Nov 10.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported

• CAS Number :

  [1228765-67-0]