Butriptyline

• Description :

  Butriptyline (Butriptylene) is an orally active tricyclic antidepressant that slightly enhances central 5-HT effects. Butriptyline does not inhibit brain norepinephrine uptake. Butriptyline can be used for depression research[1][2][3].

• Product Name Alternative :

  Butriptylene

• UNSPSC :

  12352005

• Target :

  5-HT Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/butriptyline.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC(CN(C)C)CC1C2=CC=CC=C2CCC3=C1C=CC=C3

• Molecular Formula :

  C21H27N

• Molecular Weight :

  293.45

• References & Citations :

  [1]Dulloo AG, et al. Screening of drugs for thermogenic anti-obesity properties: antidepressants. Ann Nutr Metab. 1987;31 (2) :69-80.|[2]Molinengo L, et al. The action of imipramine, amitriptyline, doxepin and butriptyline in an operant conditioning schedule. Psychopharmacologia. 1972;24 (2) :247-57.|[3]Pugsley TA, et al. Effect of butriptyline on the brain uptake mechanisms for noradrenaline and 5-hydroxytryptamine. J Pharm Pharmacol. 1974 Oct;26 (10) :778-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [35941-65-2]