Butriptyline

CAT: 0804-HY-A0175Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-A0175Size:1 Each
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Description
Butriptyline (Butriptylene) is an orally active tricyclic antidepressant that slightly enhances central 5-HT effects. Butriptyline does not inhibit brain norepinephrine uptake. Butriptyline can be used for depression research[1][2][3].
CAS Number
[35941-65-2]
Product Name Alternative
Butriptylene
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/butriptyline.html
Solubility
10 mM in DMSO
Smiles
CC(CN(C)C)CC1C2=CC=CC=C2CCC3=C1C=CC=C3
Molecular Formula
C21H27N
Molecular Weight
293.45
References & Citations
[1]Dulloo AG, et al. Screening of drugs for thermogenic anti-obesity properties: antidepressants. Ann Nutr Metab. 1987;31 (2) :69-80.|[2]Molinengo L, et al. The action of imipramine, amitriptyline, doxepin and butriptyline in an operant conditioning schedule. Psychopharmacologia. 1972;24 (2) :247-57.|[3]Pugsley TA, et al. Effect of butriptyline on the brain uptake mechanisms for noradrenaline and 5-hydroxytryptamine. J Pharm Pharmacol. 1974 Oct;26 (10) :778-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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