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Dapiprazole

CAT: 0804-HY-A0142Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-A0142Size:1 Each
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Description
Dapiprazole is a potent, selective and orally active alpha-1 adrenoceptor antagonist. Dapiprazole suppresses the opioid withdrawal symptoms. Dapiprazole is also used as eye drops for reversing mydriasis[1][2][3].
CAS Number
[72822-12-9]
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/dapiprazole.html
Solubility
10 mM in DMSO
Smiles
CC1=CC=CC=C1N2CCN(CCC3=NN=C4CCCCN43)CC2
Molecular Formula
C19H27N5
Molecular Weight
325.45
References & Citations
[1]Valeri P, et al. Effects of dapiprazole, clonidine and yohimbine on the development of dependence and withdrawal behaviour in mice. Drug Alcohol Depend. 1989 Jan;23 (1) :73-7.|[2]Allinson RW, et al. Reversal of mydriasis by dapiprazole. Ann Ophthalmol. 1990 Apr;22 (4) :131-3, 138.|[3]Hou RH, et al. Arousal and the pupil: why diazepam-induced sedation is not accompanied by miosis. Psychopharmacology (Berl) . 2007 Nov;195 (1) :41-59.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
α adrenergic receptor

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