Apixaban-d3
CAT:
804-HY-50667S1
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Apixaban-d3
- CAS Number: 1131996-12-7
- UNSPSC Description: Apixaban-d3 (BMS-562247-01-d3) is the deuterium labeled Apixaban (HY-50667)[1]. Apixaban (BMS-562247-01) is a highly selective, reversible and orally active inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively[2]. Apixaban is in development for the prevention and treatment of various thromboembolic diseases[3].
- Target Antigen: Factor Xa; Isotope-Labeled Compounds
- Type: Isotope-Labeled Compounds
- Related Pathways: Metabolic Enzyme/Protease;Others
- Field of Research: Others
- Purity: 99.0
- Solubility: 10 mM in DMSO
- Smiles: O=C1C2=C(CCN1C3=CC=C(N4C(CCCC4)=O)C=C3)C(C(N)=O)=NN2C5=CC=C(C=C5)OC([2H])([2H])[2H]
- Molecular Weight: 462.52
- References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported