Products for Research Use Only
RegisterLogin

Apixaban-d3

CAT: 0804-HY-50667S1Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-50667S1Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Apixaban-d3 (BMS-562247-01-d3) is the deuterium labeled Apixaban. Apixaban (BMS-562247-01) is a highly selective, reversible and orally active inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively[2]. Apixaban is in development for the prevention and treatment of various thromboembolic diseases[3].
CAS Number
1131996-12-7
Product Name Alternative
BMS-562247-01-d3
UNSPSC
12352005
Target
Factor Xa; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Others
Purity
99.9
Solubility
DMF : ≥ 3mg/mL|DMSO : ≥ 5mg/mL
Smiles
O=C1C2=C(CCN1C3=CC=C(N4C(CCCC4)=O)C=C3)C(C(N)=O)=NN2C5=CC=C(C=C5)OC([2H])([2H])[2H]
Molecular Formula
C25H22D3N5O4
Molecular Weight
462.52
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-50667S-01Apixaban-13C, d3
HY-I0459S-01Apixaban acid-13C, d3
HY-50667-01Apixaban
HY-50667R-01Apixaban (Standard)
HY-W086977-01Apixaban impurity 6
HY-I0464-01Apixaban impurity 3
HY-I0459-01Apixaban impurity 41
HY-I0329-01Apixaban impurity 18
HY-100655-01O-Desmethyl apixaban
HY-I0032-01Apixaban impurity 1

Alternative Products

CatalogName
TRC-A726703-50MGApixaban-d3
LAC39315-01Apixaban-13C, d3
RM-A162641-01Apixaban-13C-D3
T10349-01Apixaban 13C, d3
MBS5766070Apixaban 13C,d3
ESS0261-01Apixaban Acid-13C, D3
CS-T-103968Apixaban PG Ester-I d3
CS-T-103969Apixaban PG Ester-II d3
AR-A06799-01Apixaban Amino Acid Impurity-13C-d3
CS-O-62441N-Nitroso Apixaban Impurity B-13C, d3

Popular Products