PL1601

CAT: 0804-HY-47018Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-47018Size:1 mg

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Description

PL1601 (BCN-HS-PEG2-VA-PABC-SG3199) is a pyrrolobenzodiazepine that can be used as a agent linker of antibody-drug conjugates (ADC) [1]. PL1601 is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

CAS Number

2126805-05-6

Product Name Alternative

BCN-HS-PEG2-VA-PABC-SG3199

UNSPSC

12352005

Target

ADC Linker

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/bcn-hs-peg2-va-pabc-sg3199.html

Purity

93.66

Solubility

10 mM in DMSO

Smiles

O=C(N([C@H]1O)C(C(C(N2[C@@]1([H])CC(C)=C2)=O)=C3)=CC(OCCCCCOC(C=C(N=C[C@@](C4)([H])N(C=C4C)C5=O)C5=C6)=C6OC)=C3OC)OCC(C=C7)=CC=C7NC([C@H](C)NC([C@H](C(C)C)NC(COCCOCCN[S](NC(OC[C@@H]8[C@@]9([H])[C@]8([H])CCC#CCC9)=O)(=O)=O)=O)=O)=O

Molecular Formula

C66H83N9O18S

Molecular Weight

1322.48

References & Citations

[1]Patricius Hendrikus Cornelis VAN BERKEL. Pyrrolobenzodiazepine-antibody conjugates. Patent WO2018146199A1.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

PL1601

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