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N-Boc-dolaproine-methyl

CAT: 0804-HY-43304Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-43304Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
N-Boc-dolaproine-methyl is the amino acid residue of the pentapeptide Dolastatin 10. Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity[1].
CAS Number
164456-57-9
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Microtubule/Tubulin; Mitosis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-boc-dolaproine-methyl.html
Purity
98.23
Solubility
10 mM in DMSO
Smiles
O[C@H]([C@@H](C)C(OC)=O)[C@H]1N(C(OC(C)(C)C)=O)CCC1
Molecular Formula
C14H25NO5
Molecular Weight
287.36
Precautions
H302, H315, H319, H335
References & Citations
[1]Almeida W P, et al. An easy and stereoselective synthesis of N-Boc-dolaproine via the Baylis–Hillman reaction[J]. Tetrahedron letters, 2003, 44 (5) : 937-940.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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